What is Bioinformatics – Bioinformatics Centre - University of Copenhagen

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Bioinformatics Centre > Education > Master's degree in Bioinformatics > What is Bioinformatics

What is Bioinformatics? 

 

The core of Bioinformatics is to use computers to obtain new scientific insights in the areas of Biology and Medicine.This includes analyzing (very large!) datasets from experimental laboratories, and to design new methods and algorithms for these purposes. Current biological and medical labs use methods that produce extremely large data sets, which cannot be analyzed by hand - for instance sequencing human genomes. Thus modern biological and medical research and development cannot be done without bioinformatics.

Examples of areas where Bioinformatics is used: 

  • Design of new and better proteins, such as industrial enzymes. This could involve working out by computer simulation, what happens to the protein structure when one amino acid in the protein is replaced by another.
  • Understanding the evolutionary process by comparing species on DNA level
  • Characterizing  what genes are used in different biological processes, including disease
  • Research in how genes are regulated in a large regulatory network, where genes regulate each other.

Some few examples of bioinformatics research within the centre:

One of our recent accomplishments was the development of a probabilistic model of local protein structure. The figure shows the native protein structure on the left, the best sampled structure (using our method) next to it, and the best structures for a number of baseline methods (used for comparison) to the right.
One of our recent accomplishments was the development of a probabilistic model of local protein structure. The figure shows the native protein structure on the left, the best sampled structure (using our method) next to it, and the best structures for a number of baseline methods (used for comparison) to the right.




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