Bioinformatik Centret > Lokale nyheder
Lokale nyheder
GMD: Measuring the distance between histograms with applications on high-throughput sequencing reads
20. februar 2012
A new R package that can assess difference in distributions is now public
Predicting gene expression from epigenetics data
16. november 2011
Yun Chen and coworkers have showed the feasibility of predicting recruitment, elongation of stalling of RNA polymerase II using epigenetic data, published in BMC genomics.
Trends in Genetics review
22. september 2011
In the current issue of Trends in Genetics, Eivind Valen and Albin Sandelin reviews the different signals that are important for transcription initiation.
New postdoc opening in the Sandelin group
12. september 2011
The Sandelin group is recruiting 1-2 postdocs in applied computational biology.
New paper in PLoS ONE
25. august 2011
Xiaobei Zhao and colleagues in the Sandelin group have for the first time established how many types of promoter there are in terms of their TSS distribution. The report was published in the open access journal PLoS ONE
New paper in Nature Structural and Molecular Biology
03. august 2011
The Sandelin group and collegues have studied the origin of a class of RNA molecules in human, collectively called small RNAs. These small RNAs occur at the same places as human genes in our DNA, and their function and origin has until now been a mystery.
New paper in Nucleic Acids Research
23. maj 2011
Eivind Valen, Albin Sandelin and collaborators from Aarhus University published a characterization of non-coding transcripts that are found upstream of genes.
Paper on miRNA targetting
24. april 2011
Jiayu Wen, Brian Parker, Anders Jacobsen, and Anders Krogh published a study on the determinats of miRNA targetting in animals in the RNA journal.
New paper: Transcription factor binding sites turnover in fat cells
17. marts 2011
Mette Jörgensen, Yun Chen and Albins Sandelin published a study in BMC Genomics on how many in-vivo transcription factor binding sites that are "conserved" between human and mouse in developing fat cells.
Article on potentials of mean force
22. november 2010
After about 20 year of controversy, "potentials of mean force" as used in protein structure prediction are now finally fully understood. The theoretical insights also point to some exciting new directions in protein structure prediction. The article was published in PLoS ONE (open access).
New paper: Gene expression in epilepsies
19. oktober 2010
Together with neuroscientists from Italy, France and Germany, Troels Marstrand, Eivind Valen and Albin Sandelin have explored gee expression and regulation in epilepsies in mouse hippocampus.
New article in Genetics
08. oktober 2010
Anders Albrechtsen, Ida Moltke and Rasmus Nielsen have published a paper in Genetics entitled "Natural Selection and the Distribution of Identity-by-Descent in the Human Genome".
Article on Hawkes process models published in BMC Bioinformatics
10. september 2010
Lisbeth Carstensen and colleges published a paper describing how Hawkes models can be used for exploring relations between regulatory elements on genomes.
New article in BMC Bioinformatics
18. august 2010
The structure group publishes "Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models" in BMC Bioinformatics.
New article in Leukemia
09. juni 2010
Troels Marstrand and colleagues published a paper showing a computational framework to find candidate drugs leukemia
New article in BMC Genomics
09. juni 2010
We published a paper in BMC Genomics describing gene expression changes in spinal cord injury, a collaboration between labs at Copenhagen University and Karolinska Institute
Micro-RNA paper published in Genome Research
09. juni 2010
Anders Jakobsen and the Krogh group published the paper "Signatures of RNA binding proteins globally coupled to effective microRNA target sites" in Genome Research.
New article in BMC Bioinformatics
07. juni 2010
The structure group publishes an article on side chain modelling in BMC Bioinformatics.
Grant from The Danish Cancer Society
21. maj 2010
We secured a grant of 1,200,000 DKK from the Danish Cancer Society for studying the promoter-and splice site usage of acute myloid leukemia cells.
Postdoc openings!
21. maj 2010
We have 3 open postdoc positions in the Krogh and Sandelin groups. Deadline is 20 July 2010. Please spread to potential candidates!
Large grant from Novo Nordisk Foundation
29. april 2010
The Novo Nordisk Foundation has given the Bioinformatics Center a grant
of 15 million DKK over 5 years!
New article in Toxicological Sciences
13. april 2010
Eivind Valen and collegues have published an article in Toxicological Sciences on the AhR receptor and its binding sites
New article in BMC Bioinformatics
12. marts 2010
BMC Bioinformatics published "Mocapy++ - A toolkit for inference and learning in dynamic Bayesian networks"
Sequencing of an Ancient Human Genome
13. februar 2010
Researchers at the Bioinformatics Centre did the basic bioinformatics in the ancient genome project.
Paper in PLoS Computational Biology
26. november 2009
Eivind Valen, Albin Sandelin,Ole Winther and Anders Krogh published a paper in PLoS Computational Biology - Pattern Discovery is improved by a Discriminatory Approach
, describing how pattern discovery in promoters can be improved by
using a large negative set of actual promoters as background instead of
a statistical model.
New JASPAR release
26. november 2009
We have presented a new release of the open-access DNA binding pattern database: JASPAR . This release is almost doubling the database size. The work is summarized in the database issue of Nucleic Acids Research.
2 PhD positions in protein structure prediction
31. august 2009
Two PhD positions are available in the structural bioinformatics group. The positions are part of a project that aims at developing novel methods to determine the structure of protein ensembles.
Paper in Toxicological Sciences
23. juli 2009
Eivind Valen , Albin Sandelin and collaborators published a paper in Toxicological Sciences on the interaction between aryl hydrocarbon receptor and estrogen receptor alpha at human promoters.
Paper in PLoS Computational Biology
19. juni 2009
Jes Frellsen, Ida Moltke and Martin Thiim got their paper A probabilistic model of RNA conformational space, published in the Open Access journal PLoS computational biology.
Seminar: Manfred Sippl on protein folding
07. maj 2009
Sippl is professor of Bioinformatics at the Center of Applied Molecular Engineering (CAME) at University of Salzburg in Austria. He will hold a presentation on protein fold space and structure prediction.
Paper in Nature genetics
03. maj 2009
Several people from the Bioinformatics centre participated in a paper published in Nature genetics this month. The paper is named "The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line".
Seminar on transcription initiation
23. marts 2009
Albin Sandelin from the promoter group at the Bioinformatics centre will be holding a talk titled "A code for transcription initiation in mammalian genomes". The talk is part of a larger seminar in the Cell and Molecular Biology seminar series hosted by the Department of Biology
Paper in Bioinformatics
23. marts 2009
Thomas Hamelryck at the structure group is one of the co-authors of a recently published paper on the Biopython package, a set of freely available Python tools for computational molecular biology. Hamelryck has been part of Biopython development for many years, working on the classes that deal with macromolecular crystal structure.
Seminar by Marc Friedlander Friday 27th February
24. februar 2009
Seminar 1 in the series "What is Bioinformatics?":Discovery and profiling of small RNAs from deep sequencing data by Marc Fridländer. Room 1-2-03 in the Biocenter , Friday Feb. 27th at 14:0.
Refreshments afterwards. Everyone is welcome!
New paper published: Hippocampus promoter detection by DeepCAGE (Genome Research)
12. januar 2009
Together with scientists from Japan, Australia and Italy, Eivind Valen, Albin Sandelin and the promoter group published a paper in Genome Research describing the landscape of core promoters in mouse hippocampus.
New paper published: Drosha and DGCR8 regulate each other posttranscriptionally (Cell)
12. januar 2009
Jakob Pedersen and collegues have published a paper in Cell showing that the microRNA maturation proteins Drosha and DGCR8 regulate each other posttranscriptionally.
Apply for admission to the Master's program in Bioinformatics
08. januar 2009
Deadline to apply for admission to the Master's program in Bioinformatics is May 1st for EU students and March 15th for other students. There is no tuition fees for students from the EU.
Facebook group for the Bioinformatics Centre
08. januar 2009
We have made a group in Facebook. We hope that all former students and staff will join it. Please visit the group if you want to find people affiliated with Binf.